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Cyclamate

Cyclamate is an artificial sweetener that is still used in some countries and restricted in the United States.

Concern
High
Function
Artificial sweetener

What this is

Cyclamate is a non-nutritive artificial sweetener (~30× sweeter than sugar) used to replace sugar in “diet” or sugar-free foods. In the 1960s it was a common sweetener for low-calorie soft drinks, but it was banned in the United States in 1969 after high-dose rodent studies suggested a link to bladder cancer. Today, cyclamate is still approved in over 100 countries (as additive E952) including Canada and the European Union, with acceptable daily intake limits to ensure safety. Typical human consumption stays well below these limits, and scientific reviews have found no clear cancer risk in people. However, because a small fraction of ingested cyclamate is converted into cyclohexylamine – a metabolite that caused reproductive organ harm in animal tests at high doses – health authorities treat cyclamate with caution.

Safety Review

The critical endpoints experts review in safety assessments. This is not a prediction of harm.

Carcinogen
Reproductive/Developmental

Restaurant Usage

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State Policies

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No current state policy is listed for this ingredient in the policy tracker.

Federal Policies

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No direct federal policy is linked to this ingredient right now.